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          CALCR1/RAMP1/CRE-Luc/HEK29 GPCR細胞

          CALCR1/RAMP1/CRE-Luc/HEK29 GPCR細胞

          型    號: CBP71361
          報    價:
          分享到:

          CALCR1/RAMP1/CRE-Luc/HEK293

          CBP71361CALCR1/RAMP1/CRE-Luc/HEK29 GPCR細胞的詳細資料:

          CBP71361
          I. Background
          CALCR (Calcitonin Receptor) is a Protein Coding gene. Diseases associated with CALCR include Osteoporosis and Bone Mineral Density Quantitative Trait Locus 15. Among its related pathways are Presynaptic function of Kainate receptors and Transcription_Role of VDR in regulation of genes involved in osteoporosis. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and transmembrane signaling receptor activity.

          II. Introduction
          Host Cell:

          HEK293

          Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
          Freeze Medium:90% FBS+10% DMSO
          Culture Medium:DMEM+10%FBS+2ug/ml puromycin+5ug/ml blastcidin
          Mycoplasma Status:Negative
          Storage:Liquid nitrogen immediately upon delivery
          Transducer:Gs

          Ⅲ. Description of Host Cell Line
          Organism:Human
          Tissue:kidney
          Morphology: Epithelial
          Growth Properties: Adherent

          Ⅳ. Representative Data

           COBIOER

          Figure 1. Dose Response of Agonists in Human CALCRL/RAMP1 CRE Luc Reporter HEK293 Cells (C1).

           COBIOER

          Figure 2. Inhibtion of αCGRP induced Reporter Activity by CGRP Neutralizing Antibodies in CALCRL&RAMP1 CRE Luc HEK293 Cells.

           COBIOER

          Figure 3. Inhibition of βCGRP induced Reporter Activity by CGRP Neutralizing Antibodies in CALCRL&RAMP1 CRE Luc HEK293 Cells.







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